Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13039630 | 0.83 | ALDH1A1 (0.88) | ALDH1A1HAO1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2124073 | 0.82 | ALDH1A1 (0.58) | ALDH1A1HAO1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2124075 | 0.82 | ALDH1A1 (0.58) | ALDH1A1HAO1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL18086797 | 0.82 | KMT2A (0.54) | ALDH1A1HAO1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL18857441 | 0.81 | ALDH1A1 (0.67) | ALDH1A1HAO1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL574952 | 0.80 | ALDH1A1 (0.70) | ALDH1A1HAO1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL574953 | 0.80 | ALDH1A1 (0.70) | ALDH1A1HAO1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10846442 | 0.80 | MAPT (0.57) | RAB9ANPC1TDP1MAPTLMNA | |
| SCHEMBL10846438 | 0.80 | MAPT (0.57) | RAB9ANPC1TDP1MAPTLMNA | |
| Cinnamic Acid SCHEMBL28197287 | 0.80 | ALDH1A1 (0.51) | ALDH1A1HAO1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486528-A | ANTIULCER AGENTS, ANXIOLYTIC AGENTS | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-23 | — | — | US | disclosed |
| EP-0619299-A2 | 1-(Phenyl)-3-[omega-(amino)-alkoxyimino]-alk-1-ene derivatives, a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-10-12 | — | — | EP | disclosed |