Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | FURIN | P09958 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31331613 | 1.00 | PPARD (0.49) | PPARDPPARAHRH3HDAC1HDAC2 | |
| SCHEMBL7561155 | 1.00 | PPARD (0.49) | PPARDPPARAHRH3HDAC1HDAC2 | |
| SCHEMBL14665672 | 0.90 | HRH3 (0.57) | HRH3HDAC1HDAC2MMP3ALDH1A1 | |
| SCHEMBL22120085 | 0.90 | HRH3 (0.57) | HRH3HDAC1HDAC2MMP3ALDH1A1 | |
| SCHEMBL5522292 | 0.90 | HRH3 (0.57) | HRH3HDAC1HDAC2MMP3ALDH1A1 | |
| SCHEMBL17274247 | 0.90 | HRH3 (0.57) | HRH3HDAC1HDAC2MMP3ALDH1A1 | |
| SCHEMBL7561045 | 0.89 | PPARD (0.52) | PPARDPPARAHRH3HDAC1HDAC2 | |
| SCHEMBL9004244 | 0.89 | PPARD (0.52) | PPARDPPARAHRH3HDAC1HDAC2 | |
| SCHEMBL21391748 | 0.88 | FURIN (0.48) | PPARAHRH3ALDH1A1L3MBTL1FURIN | |
| SCHEMBL31006436 | 0.88 | FURIN (0.48) | PPARAHRH3ALDH1A1L3MBTL1FURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543267-A | Photo-induced optically anisotropic amorphous film materials from side group polymers | AGFA-GEVAERT AG (DE) | 1996-08-06 | — | — | US | disclosed |
| US-4631328-A | LIQUID CRYSTALS | BASF AKTIENGESELLSCHAFT (DE) | 1986-12-23 | — | — | US | disclosed |