Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.52 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | MMP2 | P08253 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 5/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.44 |
| ▸ | HRH2 | P25021 | 3/20 | 0.44 |
| ▸ | HRH1 | P35367 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004244 | 1.00 | PPARD (0.52) | PPARDPPARAMMP2ALDH1A1MAPT | |
| SCHEMBL410754 | 0.89 | MMP2 (0.61) | MMP2ALDH1A1MAPTMMP3MMP1 | |
| SCHEMBL31331613 | 0.89 | PPARD (0.49) | PPARDPPARAMMP2ALDH1A1MAPT | |
| SCHEMBL9004231 | 0.89 | PPARD (0.49) | PPARDPPARAMMP2ALDH1A1MAPT | |
| SCHEMBL7561155 | 0.89 | PPARD (0.49) | PPARDPPARAMMP2ALDH1A1MAPT | |
| SCHEMBL9362894 | 0.87 | ALDH1A1 (0.58) | PPARDPPARAALDH1A1RECQL | |
| SCHEMBL9362882 | 0.87 | ALDH1A1 (0.58) | PPARDPPARAALDH1A1RECQL | |
| SCHEMBL5096555 | 0.85 | MMP2 (0.67) | MMP2ALDH1A1MAPTMMP3MMP1 | |
| SCHEMBL18409045 | 0.83 | PPARD (0.52) | PPARDPPARAMMP2ALDH1A1MAPT | |
| SCHEMBL5705450 | 0.82 | MAOB (0.46) | PPARDPPARAMMP2ALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0622789-B1 | Sheet-like structures containing side chain polymers | BAYER AG (DE) | 2002-08-07 | — | — | EP | disclosed |
| US-5543267-A | Photo-induced optically anisotropic amorphous film materials from side group polymers | AGFA-GEVAERT AG (DE) | 1996-08-06 | — | — | US | disclosed |
| EP-0622789-A1 | Sheet-like structures containing side chain polymers | Agfa-Gevaert AG (DE) | 1994-11-02 | — | — | EP | disclosed |