Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | MMP14 | P50281 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | CA2 | P00918 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9090344 | 0.98 | CYP3A4 (0.58) | CYP3A4TSHRTDP1ATMMMP9 | |
| SCHEMBL21281748 | 0.95 | CYP3A4 (0.51) | CYP3A4TSHRTDP1ATMMMP9 | |
| SCHEMBL17091387 | 0.84 | CYP3A4 (0.56) | CYP3A4TSHRTDP1ATMMMP9 | |
| SCHEMBL467542 | 0.83 | CYP3A4 (0.66) | CYP3A4TSHRTDP1ATMMMP9 | |
| SCHEMBL12017280 | 0.83 | CYP3A4 (0.51) | CYP3A4TSHRTDP1ATMMMP9 | |
| SCHEMBL12639116 | 0.83 | CYP3A4 (0.51) | CYP3A4TSHRTDP1ATMMMP9 | |
| SCHEMBL16261049 | 0.83 | CA2 (0.51) | CYP3A4TSHRTDP1ATMMMP9 | |
| SCHEMBL11905467 | 0.83 | CYP3A4 (0.71) | CYP3A4TSHRTDP1ATMMMP9 | |
| SCHEMBL3765751 | 0.83 | CYP3A4 (0.71) | CYP3A4TSHRTDP1ATMMMP9 | |
| SCHEMBL1839353 | 0.83 | CYP3A4 (0.71) | CYP3A4TSHRTDP1ATMMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730585-A1 | ETHERIFIED ALKYL OR ARYLCARBAMYLMETHYLATED AMINOTRIAZINES AND CURABLE COMPOSITIONS CONTAINING THE SAME | PPG INDUSTRIES, INC. (US) | 1996-09-11 | — | — | EP | disclosed |
| US-5545696-A | FILM FORMERS IN COATINGS | PPG INDUSTRIES, INC. (US) | 1996-08-13 | — | — | US | disclosed |
| US-5536835-A | Etherified alkyl or arylcarbamylmethylated aminotriazines and curable compositions containing the same | PPG INDUSTRIES, INC. (US) | 1996-07-16 | — | — | US | disclosed |
| WO-1995014677-A1 | ETHERIFIED ALKYL OR ARYLCARBAMYLMETHYLATED AMINOTRIAZINES AND CURABLE COMPOSITIONS CONTAINING THE SAME | PPG INDUSTRIES, INC. (US) | 1995-06-01 | — | — | WO | disclosed |