SCHEMBL9004307

SCHEMBL9004307

COC(C)OC(=O)c1ccc(C(C)=O)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.48
CA2 P00918 4/20 0.48
CA12 O43570 3/20 0.48
CA7 P43166 3/20 0.48
CA9 Q16790 3/20 0.48
CA14 Q9ULX7 3/20 0.48
MAPT P10636 3/20 0.45
HPGD P15428 2/20 0.45
RAB9A P51151 2/20 0.45
PDCD1 Q15116 1/20 0.44
CD274 Q9NZQ7 1/20 0.44
CYP4F2 P78329 1/20 0.42
CYP4A11 Q02928 1/20 0.42
LMNA P02545 3/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
KMT2A Q03164 2/20 0.41
POLB P06746 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
MEN1 O00255 1/20 0.40
CYP2C9 P11712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17797792 0.92 CA1 (0.55) CA1CA2CA12CA7CA9
SCHEMBL28927209 0.86 CA1 (0.55) CA1CA2CA12CA7CA9
SCHEMBL17824411 0.85 MAPT (0.49) CA1CA2CA12CA7CA9
SCHEMBL24736750 0.83 CA1 (0.47) CA1CA2CA12CA7CA9
SCHEMBL10533713 0.83 LMNA (0.50) CA1CA2CA12CA7CA9
SCHEMBL4418738 0.82 TSHR (0.57) CA1CA2CA12CA7CA9
SCHEMBL22282993 0.82 CA12 (0.70) CA1CA2CA12CA7CA9
SCHEMBL1324998 0.80 PDCD1 (0.72) CA1CA2CA12CA7CA9
SCHEMBL14919007 0.79 LMNA (0.50) CA1CA2CA12CA7CA9
SCHEMBL12559951 0.79 CA1 (0.43) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8946557-B2 Multilayer insulated electric wire and transformer using the same FURUKAWA ELECTRIC CO., LTD. (JP) 2015-02-03 US disclosed
US-20120154099-A1 MULTILAYER INSULATED ELECTRIC WIRE AND TRANSFORMER USING THE SAME FURUKAWA ELECTRIC CO., LTD. (JP) 2012-06-21 US disclosed
US-8188370-B2 Multilayer insulated electric wire and transformer using the same FURUKAWA ELECTRIC CO., LTD. (JP) 2012-05-29 US disclosed
US-20110227691-A1 MULTILAYER INSULATED ELECTRIC WIRE AND TRANSFORMER USING THE SAME FURUKAWA ELECTRIC CO., LTD. (JP) 2011-09-22 US disclosed
US-20110174520-A1 INSULATED ELECTRIC WIRE THE FURUKAWA ELECTRIC CO., LTD. (JP) 2011-07-21 US disclosed
US-20110068302-A1 SHAPED ARTICLE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-03-24 US disclosed