SCHEMBL9004328

SCHEMBL9004328

C=C(C)C(=O)COOC(=O)CCC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 4/20 0.38
KDM6B O15054 2/20 0.38
KDM5C P41229 2/20 0.38
PHF8 Q9UPP1 2/20 0.38
KDM2A Q9Y2K7 2/20 0.38
LMNA P02545 2/20 0.37
SLC15A2 Q16348 1/20 0.37
ALKBH5 Q6P6C2 1/20 0.33
SUCNR1 Q9BXA5 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MAPK1 P28482 1/20 0.32
SLC13A3 Q8WWT9 1/20 0.32
OR51E2 Q9H255 1/20 0.32
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL148043 0.84 EGLN1 (0.37) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL94605 0.78 LMNA (0.45) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL1690886 0.76 LMNA (0.43) EGLN1KDM6BKDM5CPHF8KDM2A
Ammonia Solution, Strong SCHEMBL11544655 0.76 LMNA (0.43) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL11544042 0.76 LMNA (0.43) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL11393555 0.76 LMNA (0.43) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL148040 0.75 TSHR (0.32) TSHR
SCHEMBL7769287 0.74 PHF8 (0.45) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL11743450 0.74 LMNA (0.41) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL11742609 0.74 LMNA (0.41) EGLN1KDM6BKDM5CPHF8KDM2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4065423-A Paper coating latex compositions containing copolymers of monovinylidene aromatic monomer, aliphatic conjugated diene and an aryloyloxycarboxylic acid monomer UNIROYAL, INC. (US) 1977-12-27 US claimed
US-5492787-A DEVELOPMENT OF ELECTROSTATIC IMAGES SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1996-02-20 US disclosed