Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.59 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.59 |
| ▸ | DRD2 | P14416 | 3/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
| ▸ | IGF1R | P08069 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9249869 | 0.95 | ACHE (0.68) | ACHEADRA1AADRA1BDRD2HTR2A | |
| SCHEMBL9256653 | 0.94 | ACHE (0.66) | ACHEADRA1AADRA1BDRD2HTR2A | |
| SCHEMBL9254406 | 0.90 | ACHE (0.73) | ACHEADRA1AADRA1BDRD2HTR2A | |
| SCHEMBL22252849 | 0.90 | ACHE (0.78) | ACHEADRA1AADRA1BDRD2HTR2A | |
| SCHEMBL22252679 | 0.86 | ACHE (0.88) | ACHEADRA1AADRA1BDRD2HTR2A | |
| SCHEMBL7267063 | 0.84 | ACHE (0.69) | ACHEADRA1AADRA1BDRD2HTR2A | |
| SCHEMBL7395278 | 0.84 | ACHE (0.69) | ACHEADRA1AADRA1BDRD2HTR2A | |
| SCHEMBL16226783 | 0.84 | ACHE (0.69) | ACHEADRA1AADRA1BDRD2HTR2A | |
| SCHEMBL4249527 | 0.84 | DRD3 (0.61) | ADRA1BDRD2HTR2ADRD3LMNA | |
| SCHEMBL16227246 | 0.83 | ACHE (0.68) | ACHEADRA1AADRA1BDRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733040-A1 | PIPERAZINE-SUBSTITUTED PYRROLOANTHRACENE AS IMMUNO-MODERATORS | BAYER AG (DE) | 1996-09-25 | — | — | EP | disclosed |
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| US-5459143-A | Immunomodulating agents | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-17 | — | — | US | disclosed |
| WO-1995015946-A1 | PIPERAZINE-SUBSTITUTED PYRROLOANTHRACENE AS IMMUNO-MODERATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1995-06-15 | — | — | WO | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |