SCHEMBL9004471

SCHEMBL9004471

CCOP(=O)(OCC)C(c1ccc(C(P(=O)(O)O)P(=O)(O)O)cc1)P(=O)(OCC)OCC

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.50
GAA P10253 2/20 0.49
SRC P12931 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.41
ALDH1A1 P00352 2/20 0.40
MAPT P10636 2/20 0.40
LMNA P02545 1/20 0.40
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
KDM4E B2RXH2 1/20 0.37
PGK1 P00558 2/20 0.36
PGK2 P07205 2/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9004470 0.95 POLB (0.46) POLBGAASRCL3MBTL1ALDH1A1
SCHEMBL9004484 0.91 POLB (0.43) POLBGAASRCL3MBTL1ALDH1A1
SCHEMBL9169133 0.89 POLB (0.44) POLBGAASRCL3MBTL1ALDH1A1
SCHEMBL5664657 0.85 POLB (0.50) POLBGAAL3MBTL1ALDH1A1MAPT
SCHEMBL12479086 0.85 POLB (0.41) POLBGAASRCL3MBTL1ALDH1A1
SCHEMBL7088667 0.83 CA12 (0.49) POLBGAAL3MBTL1ALDH1A1MAPT
SCHEMBL5754677 0.81 KMT2A (0.55) POLBGAAL3MBTL1ALDH1A1MAPT
SCHEMBL7160912 0.81 POLB (0.68) POLBSRCALDH1A1MAPTLMNA
SCHEMBL4320046 0.80 POLB (0.40) POLBGAASRCL3MBTL1MAPT
SCHEMBL7828967 0.79 POLB (0.44) POLBGAAL3MBTL1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0442097-B1 Poly(arylenevinylene siloxanes) CONSORTIUM ELEKTROCHEM IND (DE) 1996-10-09 EP disclosed
US-5185419-A POLY(ARYLENEVINYLENESILOXANES) COMPOUNDS CONSORTIUM FUR ELEKTROCHEMISCHE GMBH (DE) 1993-02-09 US disclosed
EP-0442097-A2 Poly(arylenevinylene siloxanes) Consortium für elektrochemische Industrie GmbH (DE) 1991-08-21 EP disclosed
US-4423203-A Electrically photosensitive polymers containing vinylene-1,4-phenylene-imino-1,4-phenylene-vinylenearylene groups EASTMAN KODAK COMPANY (US) 1983-12-27 US disclosed