SCHEMBL9004546

SCHEMBL9004546

ClCC(Cl)CC[Si](Cl)(Cl)Cl

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.36
TSHR P16473 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4073604 0.74 ALDH1A1 (0.31) TSHRTDP1
SCHEMBL7516996 0.73 TP53 (0.50) TP53TSHRTDP1
SCHEMBL7608550 0.71
SCHEMBL7608560 0.69
SCHEMBL4733495 0.69 TP53 (0.36) TP53TSHRTDP1
SCHEMBL9245791 0.69 TP53 (0.31) TP53TSHRTDP1
SCHEMBL7525524 0.67 TP53 (0.44) TP53TSHRTDP1
SCHEMBL7528143 0.67 TP53 (0.44) TP53TSHRTDP1
SCHEMBL1072967 0.67
SCHEMBL2450401 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0350600-B1 Process for the preparation of pure 3-butenyltriorganyloxysilanes DEGUSSA (DE) 1995-07-12 EP claimed
EP-0350600-A2 Process for the preparation of pure 3-butenyltriorganyloxysilanes Degussa Aktiengesellschaft (DE) 1990-01-17 EP claimed
JP-2069487-A None JP disclosed
EP-0497278-B1 Organopentasiloxane and method for its preparation DOW CORNING TORAY SILICONE (JP) 1996-10-09 EP disclosed
EP-0350600-B1 Process for the preparation of pure 3-butenyltriorganyloxysilanes DEGUSSA (DE) 1995-07-12 EP disclosed
US-5164501-A Vulcanization of silica filled rubbers DEGUSSA AG (DE) 1992-11-17 US disclosed
US-5073644-A Reinforced rubber additive DEGUSSA-HULS AKTIENGESELLSCHAFT (DE) 1991-12-17 US disclosed
JP-H0269487-A PRODUCTION OF PURE 3-BUTENYLORGANYLOXYSILANE, INTERMEDIATE FOR PRODUCING THE SAME AND RUBBER MIXTURE CONTAINING THE SAME DEGUSSA AG 1990-03-08 JP disclosed
EP-0350600-A2 Process for the preparation of pure 3-butenyltriorganyloxysilanes Degussa Aktiengesellschaft (DE) 1990-01-17 EP disclosed