Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7180366 | 0.92 | CYP3A4 (0.58) | CYP3A4 | |
| SCHEMBL7443468 | 0.92 | CYP3A4 (0.58) | CYP3A4 | |
| SCHEMBL8853637 | 0.90 | CYP3A4 (0.63) | CYP3A4 | |
| SCHEMBL7309108 | 0.90 | CYP3A4 (0.63) | CYP3A4 | |
| SCHEMBL4683833 | 0.90 | CYP3A4 (0.63) | CYP3A4 | |
| SCHEMBL4677833 | 0.89 | CYP3A4 (0.61) | CYP3A4 | |
| SCHEMBL9065625 | 0.89 | CYP3A4 (0.61) | CYP3A4 | |
| SCHEMBL9064880 | 0.89 | CYP3A4 (0.61) | CYP3A4 | |
| SCHEMBL9004985 | 0.87 | CYP3A4 (0.60) | CYP3A4 | |
| SCHEMBL9005118 | 0.86 | CYP3A4 (0.49) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541321-A | Process for the preparation of a substituted diaminoalcohol | ABBOTT LABORATORIES (US) | 1996-07-30 | — | — | US | disclosed |
| US-5541320-A | Process for the preparation of a substituted diaminoalcohol | ABBOT LABORATORIES (US) | 1996-07-30 | — | — | US | disclosed |
| US-5436339-A | Process for the preparation of a substituted diaminoalcohol | ABBOTT LABORATORIES (US) | 1995-07-25 | — | — | US | disclosed |