⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27801025 | 0.72 | — | — | |
| SCHEMBL12395684 | 0.70 | — | — | |
| SCHEMBL26972518 | 0.67 | GBA1 (0.36) | — | |
| SCHEMBL24853994 | 0.66 | — | — | |
| SCHEMBL11998896 | 0.66 | ALDH1A1 (0.33) | — | |
| SCHEMBL24853988 | 0.66 | SCN1A (0.38) | — | |
| SCHEMBL9005341 | 0.64 | — | — | |
| SCHEMBL24854202 | 0.64 | GBA1 (0.42) | — | |
| SCHEMBL17663698 | 0.63 | KMT2A (0.50) | — | |
| SCHEMBL9675535 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576320-A | 1-heteruarylazetidines and -pyrrolidines, process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1996-11-19 | — | — | US | disclosed |
| US-5565474-A | 1-heteroarylazetidines and -pyrrolidines process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1996-10-15 | — | — | US | disclosed |