Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.72 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | FBP1 | P09467 | 2/20 | 0.65 |
| ▸ | VCP | P55072 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.58 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9662892 | 1.00 | NFE2L2 (0.72) | NFE2L2CYP19A1MAPTPOLBTDP1 | |
| SCHEMBL15498134 | 0.89 | NFE2L2 (0.89) | NFE2L2CYP19A1MAPTPOLBTDP1 | |
| SCHEMBL11301074 | 0.85 | CYP19A1 (0.93) | NFE2L2CYP19A1MAPTPOLBTDP1 | |
| SCHEMBL11301072 | 0.85 | CYP19A1 (0.93) | NFE2L2CYP19A1MAPTPOLBTDP1 | |
| SCHEMBL1405314 | 0.84 | NFE2L2 (1.00) | NFE2L2CYP19A1MAPTPOLBTDP1 | |
| SCHEMBL1405312 | 0.84 | NFE2L2 (1.00) | NFE2L2CYP19A1MAPTPOLBTDP1 | |
| SCHEMBL5894264 | 0.81 | NFE2L2 (0.75) | NFE2L2CYP19A1MAPTPOLBTDP1 | |
| SCHEMBL5894256 | 0.81 | NFE2L2 (0.75) | NFE2L2CYP19A1MAPTPOLBTDP1 | |
| SCHEMBL6803950 | 0.80 | NFE2L2 (0.73) | NFE2L2CYP19A1MAPTPOLBTDP1 | |
| SCHEMBL6797334 | 0.80 | NFE2L2 (0.68) | NFE2L2CYP19A1MAPTPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516409-B1 | Tetravinylpyrazine compound, method for preparing same and electroluminescent element and non-linear optical material using same | MITSUI TOATSU CHEMICALS (JP) | 1996-09-11 | — | — | EP | disclosed |
| US-5416213-A | Tetravinylpyrazine compound, method for preparing same and electroluminescent element and non-linear optical material using same | MITSUI TOATSU CHEMICALS, INC. (JP) | 1995-05-16 | — | — | US | disclosed |
| EP-0516409-A2 | Tetravinylpyrazine compound, method for preparing same and electroluminescent element and non-linear optical material using same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-12-02 | — | — | EP | disclosed |