Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 16/20 | 0.89 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.59 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9005581 | 0.88 | PTGIR (0.70) | PTGIRTBXAS1 | |
| SCHEMBL9051699 | 0.83 | PTGIR (0.69) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL9155513 | 0.83 | PTGIR (0.69) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL9155480 | 0.82 | PTGIR (0.68) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL8858587 | 0.81 | PTGIR (0.72) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL9047729 | 0.81 | PTGIR (0.66) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL9048590 | 0.81 | PTGIR (0.71) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL9005686 | 0.81 | PTGIR (0.84) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL9048216 | 0.81 | PTGIR (0.71) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL9005777 | 0.81 | PTGIR (0.84) | PTGIRTBXAS1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0578847-B1 | Fused benzeneoxyacetic acid derivatives and their use as PG12 antagonists | ONO PHARMACEUTICAL CO (JP) | 1996-10-09 | — | — | EP | claimed |
| EP-0578847-A1 | Fused benzeneoxyacetic acid derivatives and their use as PG12 antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-01-19 | — | — | EP | claimed |
| EP-0578847-B1 | Fused benzeneoxyacetic acid derivatives and their use as PG12 antagonists | ONO PHARMACEUTICAL CO (JP) | 1996-10-09 | — | — | EP | disclosed |
| US-5461045-A | Treating thrombosis, arteriosclerosis, ischemic heart diseases, gastric ulcer and hypertension | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0578847-A1 | Fused benzeneoxyacetic acid derivatives and their use as PG12 antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-01-19 | — | — | EP | disclosed |