Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 18/20 | 0.84 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9005777 | 1.00 | PTGIR (0.84) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL9005755 | 0.94 | PTGIR (0.74) | PTGIRTBXAS1 | |
| SCHEMBL9005645 | 0.94 | PTGIR (0.74) | PTGIRTBXAS1 | |
| SCHEMBL9005725 | 0.82 | PTGIR (0.57) | PTGIR | |
| SCHEMBL9005722 | 0.82 | PTGIR (0.57) | PTGIR | |
| SCHEMBL9005583 | 0.81 | PTGIR (0.89) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL9005666 | 0.79 | PTGIR (1.00) | PTGIRTBXAS1 | |
| SCHEMBL9005672 | 0.79 | PTGIR (1.00) | PTGIRTBXAS1 | |
| SCHEMBL9047729 | 0.78 | PTGIR (0.66) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL9050868 | 0.77 | PTGIR (0.64) | PTGIRTBXAS1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0578847-B1 | Fused benzeneoxyacetic acid derivatives and their use as PG12 antagonists | ONO PHARMACEUTICAL CO (JP) | 1996-10-09 | — | — | EP | claimed |
| EP-0578847-A1 | Fused benzeneoxyacetic acid derivatives and their use as PG12 antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-01-19 | — | — | EP | claimed |