Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | KMO | O15229 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.49 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9368992 | 0.85 | SRD5A2 (0.60) | AKR1C3NPC1POLBCYP2C9RAB9A | |
| SCHEMBL21234444 | 0.84 | AKR1C3 (0.70) | AKR1C3NPC1POLBCYP2C9RAB9A | |
| SCHEMBL9374242 | 0.83 | PPARA (0.56) | AKR1C3CYP2C9SRD5A2ADRB3LMNA | |
| SCHEMBL18713541 | 0.83 | FFAR1 (0.49) | KDM4EALDH1A1SMN1; SMN2KMT2AFFAR1 | |
| SCHEMBL1042631 | 0.83 | AKR1C3 (0.92) | AKR1C3NPC1POLBCYP2C9RAB9A | |
| SCHEMBL30266789 | 0.83 | AKR1C3 (0.92) | AKR1C3NPC1POLBCYP2C9RAB9A | |
| SCHEMBL6682568 | 0.82 | AKR1C3 (0.52) | AKR1C3NPC1POLBCYP2C9RAB9A | |
| SCHEMBL9374246 | 0.82 | KMT2A (0.59) | NR4A2KMT2AFFAR1NR4A1NR4A3 | |
| SCHEMBL27888993 | 0.81 | AKR1C3 (0.66) | AKR1C3NPC1POLBCYP2C9RAB9A | |
| SCHEMBL4320685 | 0.81 | AKR1C3 (0.96) | AKR1C3NPC1POLBCYP2C9RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579223-B1 | Carboxylic acid derivatives having 5 alpha-reductase inhibitory activity | MITSUBISHI CHEM CORP (JP) | 1996-10-09 | — | — | EP | disclosed |
| US-5385917-A | Treating androgen dependent diseases | MITSUBISHI KASEI CORPORATION (JP) | 1995-01-31 | — | — | US | disclosed |
| EP-0579223-A1 | Carboxylic acid derivatives having 5 alpha-reductase inhibitory activity | Mitsubishi Chemical Corporation (JP) | 1994-01-19 | — | — | EP | disclosed |