Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | RXRA | P19793 | 2/20 | 0.53 |
| ▸ | RXRB | P28702 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.50 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.50 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.50 |
| ▸ | RARB | P10826 | 2/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL452233 | 0.89 | PTGS1 (0.60) | MAPK1KMT2APTGS1PTGS2LMNA | |
| SCHEMBL27959311 | 0.89 | PTGS1 (0.60) | MAPK1KMT2APTGS1PTGS2LMNA | |
| SCHEMBL9374371 | 0.86 | HPGD (0.66) | KMT2APTGS1PTGS2LMNACYP2C9 | |
| SCHEMBL9348933 | 0.85 | RXRA (0.73) | SRD5A2MAPK1PARP10RXRARXRB | |
| SCHEMBL1447047 | 0.85 | PTGS2 (0.45) | SRD5A2PTGS1PTGS2LMNACYP2C9 | |
| SCHEMBL9005585 | 0.85 | AKR1C3 (0.64) | SRD5A2KMT2ALMNACYP2C9AKR1C3 | |
| SCHEMBL9369118 | 0.84 | ADRB3 (0.56) | KMT2ARXRARXRBPTGS1PTGS2 | |
| SCHEMBL4575613 | 0.83 | SLC6A4 (0.48) | PTGS1PTGS2LMNACYP2C9AKR1C3 | |
| SCHEMBL9597497 | 0.83 | FFAR1 (0.56) | SRD5A2MAPK1KMT2ARXRARXRB | |
| SCHEMBL9336515 | 0.83 | FFAR1 (0.56) | SRD5A2MAPK1KMT2ARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600084-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |
| WO-1993003012-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-18 | — | — | WO | disclosed |