Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.58 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.53 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29505911 | 0.92 | EPHX2 (0.65) | EPHX2GRIK1GRIA2AKR1C3OPRK1 | |
| SCHEMBL930213 | 0.86 | EPHX2 (0.59) | EPHX2GRIK1GRIA2AKR1C3OPRK1 | |
| SCHEMBL30162751 | 0.86 | EPHX2 (0.59) | EPHX2GRIK1GRIA2AKR1C3OPRK1 | |
| SCHEMBL931435 | 0.86 | EPHX2 (0.59) | EPHX2GRIK1GRIA2AKR1C3OPRK1 | |
| SCHEMBL931638 | 0.84 | EPHX2 (0.57) | EPHX2GRIK1GRIA2AKR1C3OPRK1 | |
| SCHEMBL9005535 | 0.84 | EPHX2 (0.57) | EPHX2GRIK1GRIA2AKR1C3OPRK1 | |
| SCHEMBL30575465 | 0.84 | EPHX2 (0.57) | EPHX2GRIK1GRIA2AKR1C3OPRK1 | |
| SCHEMBL930820 | 0.84 | EPHX2 (0.57) | EPHX2GRIK1GRIA2AKR1C3OPRK1 | |
| SCHEMBL9005707 | 0.84 | EPHX2 (0.55) | EPHX2GRIK1GRIA2AKR1C3OPRK1 | |
| SCHEMBL9005514 | 0.84 | EPHX2 (0.55) | EPHX2GRIK1GRIA2AKR1C3OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579223-B1 | Carboxylic acid derivatives having 5 alpha-reductase inhibitory activity | MITSUBISHI CHEM CORP (JP) | 1996-10-09 | — | — | EP | disclosed |
| US-5385917-A | Treating androgen dependent diseases | MITSUBISHI KASEI CORPORATION (JP) | 1995-01-31 | — | — | US | disclosed |
| EP-0579223-A1 | Carboxylic acid derivatives having 5 alpha-reductase inhibitory activity | Mitsubishi Chemical Corporation (JP) | 1994-01-19 | — | — | EP | disclosed |