Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 15/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9005623 | 1.00 | PTGIR (0.45) | PTGIRMTNR1AMTNR1BCA1CA2 | |
| SCHEMBL8414237 | 0.87 | PTGIR (0.45) | PTGIRMTNR1AMTNR1BCA1CA2 | |
| SCHEMBL9005729 | 0.87 | PTGIR (0.45) | PTGIRMTNR1AMTNR1BCA1CA2 | |
| SCHEMBL9017314 | 0.82 | MTNR1A (0.50) | PTGIRMTNR1AMTNR1BCA1CA2 | |
| SCHEMBL9017305 | 0.80 | MTNR1A (0.48) | PTGIRMTNR1AMTNR1BCA1CA2 | |
| SCHEMBL8576525 | 0.80 | PTGIR (0.62) | PTGIR | |
| SCHEMBL8488188 | 0.77 | MTNR1A (0.60) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL10464119 | 0.77 | MTNR1A (0.74) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL8576529 | 0.77 | MTNR1A (0.48) | PTGIRMTNR1AMTNR1BCA1CA2 | |
| SCHEMBL9005706 | 0.77 | PTGIR (0.47) | PTGIRDRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0578847-B1 | Fused benzeneoxyacetic acid derivatives and their use as PG12 antagonists | ONO PHARMACEUTICAL CO (JP) | 1996-10-09 | — | — | EP | disclosed |
| US-5461045-A | Treating thrombosis, arteriosclerosis, ischemic heart diseases, gastric ulcer and hypertension | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0578847-A1 | Fused benzeneoxyacetic acid derivatives and their use as PG12 antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-01-19 | — | — | EP | disclosed |