SCHEMBL9005652

SCHEMBL9005652

CCOC(=O)COc1cccc2c1CCC(CO)C2

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGIR P43119 20/20 0.52
PTGDR Q13258 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8487292 0.91 PTGIR (0.53) PTGIRPTGDR
SCHEMBL9005649 0.89 PTGIR (0.54) PTGIR
SCHEMBL8524475 0.87 PTGIR (0.47) PTGIR
SCHEMBL9005727 0.87 PTGIR (0.50) PTGIRPTGDR
SCHEMBL8524473 0.85 PTGIR (0.45) PTGIR
SCHEMBL8414260 0.84 PTGIR (0.65) PTGIRPTGDR
SCHEMBL9005706 0.84 PTGIR (0.47) PTGIR
SCHEMBL9005622 0.82 PTGIR (0.64) PTGIR
SCHEMBL7778633 0.82 PTGIR (0.80) PTGIRPTGDR
SCHEMBL7772432 0.80 PTGIR (0.66) PTGIRPTGDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0578847-B1 Fused benzeneoxyacetic acid derivatives and their use as PG12 antagonists ONO PHARMACEUTICAL CO (JP) 1996-10-09 EP disclosed
US-5461045-A Treating thrombosis, arteriosclerosis, ischemic heart diseases, gastric ulcer and hypertension ONO PHARMACEUTICAL CO., LTD. (JP) 1995-10-24 US disclosed
EP-0578847-A1 Fused benzeneoxyacetic acid derivatives and their use as PG12 antagonists ONO PHARMACEUTICAL CO., LTD. (JP) 1994-01-19 EP disclosed