Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 20/20 | 0.80 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7776687 | 0.91 | PTGIR (0.82) | PTGIRPTGDRPTGER1PTGER3 | |
| SCHEMBL7772432 | 0.91 | PTGIR (0.66) | PTGIRPTGDRPTGER1PTGER3 | |
| SCHEMBL7772466 | 0.89 | PTGIR (1.00) | PTGIRPTGDRPTGER1PTGER3 | |
| SCHEMBL7779671 | 0.85 | PTGIR (0.77) | PTGIRPTGDR | |
| SCHEMBL7713222 | 0.83 | PTGIR (0.89) | PTGIRPTGDRPTGER1PTGER3 | |
| SCHEMBL9005622 | 0.82 | PTGIR (0.64) | PTGIR | |
| SCHEMBL9005652 | 0.82 | PTGIR (0.52) | PTGIRPTGDR | |
| SCHEMBL9017276 | 0.80 | PTGIR (0.52) | PTGIRPTGDRPTGER1PTGER3 | |
| SCHEMBL7778570 | 0.80 | PTGIR (0.52) | PTGIRPTGDRPTGER1PTGER3 | |
| SCHEMBL7776682 | 0.80 | PTGIR (0.52) | PTGIRPTGDRPTGER1PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749424-B1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-12 | — | — | EP | disclosed |
| EP-0749424-A1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | EP | disclosed |
| WO-1995024393-A1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-14 | — | — | WO | disclosed |