Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.62 |
| ▸ | DRD2 | P14416 | 9/20 | 0.60 |
| ▸ | DRD3 | P35462 | 9/20 | 0.60 |
| ▸ | DRD4 | P21917 | 4/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | DRD5 | P21918 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7776686 | 0.85 | DRD2 (0.63) | CYP19A1DRD2DRD3DRD4HTR1A | |
| SCHEMBL3174365 | 0.84 | CYP19A1 (0.59) | CYP19A1DRD2DRD3HTR1A | |
| Bromide SCHEMBL9688708 | 0.83 | DRD2 (0.61) | CYP19A1DRD2DRD3DRD4HTR1A | |
| SCHEMBL29062570 | 0.82 | DRD2 (0.59) | CYP19A1DRD2DRD3DRD4HTR1A | |
| SCHEMBL29062621 | 0.82 | DRD2 (0.59) | CYP19A1DRD2DRD3DRD4HTR1A | |
| SCHEMBL8413532 | 0.81 | CYP19A1 (0.57) | CYP19A1DRD2DRD3DRD4HTR1A | |
| SCHEMBL7777377 | 0.78 | CYP19A1 (0.64) | CYP19A1DRD2DRD3DRD4CA1 | |
| SCHEMBL1261038 | 0.77 | DRD2 (0.66) | CYP19A1DRD2DRD3DRD4HTR1A | |
| SCHEMBL13487690 | 0.77 | DRD2 (0.66) | CYP19A1DRD2DRD3DRD4HTR1A | |
| SCHEMBL8410457 | 0.76 | CA1 (0.52) | CYP19A1DRD2DRD3DRD4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0578847-B1 | Fused benzeneoxyacetic acid derivatives and their use as PG12 antagonists | ONO PHARMACEUTICAL CO (JP) | 1996-10-09 | — | — | EP | disclosed |
| US-5461045-A | Treating thrombosis, arteriosclerosis, ischemic heart diseases, gastric ulcer and hypertension | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0578847-A1 | Fused benzeneoxyacetic acid derivatives and their use as PG12 antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-01-19 | — | — | EP | disclosed |