Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 4/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8943415 | 0.87 | NPC1 (0.45) | HTTNPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL8518197 | 0.84 | HTT (0.58) | HTTALDH1A1L3MBTL1RARBHSD17B10 | |
| Hydrochloric Acid SCHEMBL8517634 | 0.82 | HTT (0.57) | HTTALDH1A1L3MBTL1RARBHSD17B10 | |
| SCHEMBL8770703 | 0.82 | HTT (0.63) | HTTALDH1A1L3MBTL1HSD17B10SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9243417 | 0.81 | HTT (0.61) | HTTALDH1A1L3MBTL1HSD17B10SMN1; SMN2 | |
| SCHEMBL6673551 | 0.80 | HTT (0.39) | HTTALDH1A1L3MBTL1RARBPDE4B | |
| SCHEMBL8861877 | 0.77 | HTT (0.57) | HTTALDH1A1L3MBTL1HSD17B10RAB9A | |
| SCHEMBL9501910 | 0.76 | SMN1; SMN2 (0.38) | HTTALDH1A1L3MBTL1HSD17B10PDE4B | |
| Hydrochloric Acid SCHEMBL8861930 | 0.75 | HTT (0.56) | HTTALDH1A1L3MBTL1HSD17B10RAB9A | |
| SCHEMBL8586984 | 0.75 | RARB (0.55) | ALDH1A1L3MBTL1RARBHCAR3CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434297-B1 | Optically active aromatic compounds, preparation process thereof, and liquid crystal compositions and elements | SUMITOMO CHEMICAL CO (JP) | 1996-10-16 | — | — | EP | disclosed |
| US-5238598-A | Having trifluoromethyl group; high speed response | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-08-24 | — | — | US | disclosed |
| EP-0434297-A2 | Optically active aromatic compounds, preparation process thereof, and liquid crystal compositions and elements | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-06-26 | — | — | EP | disclosed |