Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6673551 | 0.91 | HTT (0.39) | SMN1; SMN2TP53ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL10578448 | 0.82 | MAPT (0.44) | SMN1; SMN2TP53ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL11389973 | 0.80 | MAPT (0.51) | SMN1; SMN2TP53ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL9429911 | 0.79 | ALDH1A1 (0.44) | SMN1; SMN2TP53ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL8943415 | 0.78 | NPC1 (0.45) | SMN1; SMN2TP53HTTKMT2ARAB9A | |
| SCHEMBL9245694 | 0.77 | NPC1 (0.65) | SMN1; SMN2TP53ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL10582715 | 0.77 | MAPT (0.43) | SMN1; SMN2TP53ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL9005809 | 0.76 | HTT (0.52) | SMN1; SMN2ALDH1A1HTTRAB9ANPC1 | |
| SCHEMBL9505062 | 0.76 | SNCA (0.47) | SMN1; SMN2TP53ALDH1A1CYP3A4TSHR | |
| SCHEMBL8645132 | 0.74 | SMN1; SMN2 (0.41) | SMN1; SMN2TP53ALDH1A1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260077-B1 | PHENYL PYRIMIDINE COMPOUND AND LIQUID CRYSTALLINE COMPOSITION | AJINOMOTO CO., INC. (JP) | 1993-05-26 | — | — | EP | disclosed |
| EP-0244129-B1 | OPTICALLY ACTIVE COMPOUND AND LIQUID CRYSTALLINE COMPOSITION | AJINOMOTO CO., INC. (JP) | 1992-11-11 | — | — | EP | disclosed |
| US-4892676-A | FERROELECTRIC, HIGH SPEED RESPONSE | AJINOMOTO CO., INC. (JP) | 1990-01-09 | — | — | US | disclosed |
| US-4880561-A | Optically active compound and liquid crystalline composition | AJINOMOTO CO., INC. (JP) | 1989-11-14 | — | — | US | disclosed |