Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.50 |
| ▸ | PPARG | P37231 | 17/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9005919 | 0.90 | PPARG (0.54) | PPARAPPARG | |
| SCHEMBL9005899 | 0.87 | PPARA (0.58) | PPARAPPARGPTPN1 | |
| SCHEMBL9005915 | 0.84 | PPARA (0.51) | PPARAPPARGCYP2C9KCNH2PTPN1 | |
| SCHEMBL9091541 | 0.81 | PPARG (0.52) | PPARAPPARG | |
| SCHEMBL9263906 | 0.81 | PPARG (0.55) | PPARAPPARGCYP2C9KCNH2PTPN1 | |
| SCHEMBL9176979 | 0.79 | PPARG (0.66) | PPARAPPARGCYP2C9KCNH2 | |
| SCHEMBL9175578 | 0.79 | PPARG (0.56) | PPARAPPARGCYP2C9KCNH2 | |
| SCHEMBL9005900 | 0.79 | PPARG (0.60) | PPARAPPARG | |
| SCHEMBL9156966 | 0.76 | PPARA (0.61) | PPARAPPARG | |
| SCHEMBL9005933 | 0.76 | PPARG (0.54) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541205-A | ANTIINFLAMMATORY AGENTS; ANTIASTHMA AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-07-30 | — | — | US | disclosed |
| US-5428048-A | Aryl-N-hydroxyureas as inhibitors of 5-lipoxygenase and anto-arteriosclerotic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-06-27 | — | — | US | disclosed |