Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.51 |
| ▸ | PPARG | P37231 | 15/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9005899 | 0.86 | PPARA (0.58) | PPARAPPARGPTPN1 | |
| SCHEMBL9005897 | 0.84 | PPARA (0.50) | PPARAPPARGPTPN1CYP2C9KCNH2 | |
| SCHEMBL9175578 | 0.80 | PPARG (0.56) | PPARAPPARGCYP2C9KCNH2 | |
| SCHEMBL9263906 | 0.79 | PPARG (0.55) | PPARAPPARGPTPN1CYP2C9KCNH2 | |
| SCHEMBL9176979 | 0.78 | PPARG (0.66) | PPARAPPARGCYP2C9KCNH2 | |
| SCHEMBL9005900 | 0.76 | PPARG (0.60) | PPARAPPARGPPARD | |
| SCHEMBL9156966 | 0.75 | PPARA (0.61) | PPARAPPARGPPARD | |
| SCHEMBL9005933 | 0.75 | PPARG (0.54) | PPARAPPARGPPARD | |
| SCHEMBL9005936 | 0.74 | PPARG (0.64) | PPARAPPARGCYP2C9KCNH2 | |
| SCHEMBL8859196 | 0.73 | PPARG (0.72) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541205-A | ANTIINFLAMMATORY AGENTS; ANTIASTHMA AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-07-30 | — | — | US | disclosed |
| US-5428048-A | Aryl-N-hydroxyureas as inhibitors of 5-lipoxygenase and anto-arteriosclerotic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-06-27 | — | — | US | disclosed |