Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.57 |
| ▸ | PPARG | P37231 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 10/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9005921 | 0.89 | TP53 (0.52) | PPARAPPARGTP53LMNAMAPT | |
| SCHEMBL9258919 | 0.79 | PPARG (0.53) | PPARAPPARGTP53LMNAMAPT | |
| SCHEMBL9173584 | 0.79 | PPARA (0.66) | PPARAPPARGTP53MAPTKDM4E | |
| SCHEMBL9178076 | 0.79 | PPARA (0.66) | PPARAPPARGTP53MAPT | |
| SCHEMBL9005938 | 0.78 | TP53 (0.45) | TP53LMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL9177913 | 0.78 | PPARA (0.59) | PPARAPPARGTP53LMNAMAPT | |
| SCHEMBL9176979 | 0.73 | PPARG (0.66) | PPARAPPARG | |
| SCHEMBL5015483 | 0.71 | PPARD (0.56) | PPARAPPARGTP53LMNAMAPT | |
| SCHEMBL9594793 | 0.71 | PPARA (0.55) | PPARAPPARGTP53LMNAMAPT | |
| SCHEMBL10518087 | 0.70 | PPARA (0.58) | PPARAPPARGTP53LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541205-A | ANTIINFLAMMATORY AGENTS; ANTIASTHMA AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-07-30 | — | — | US | claimed |
| US-5428048-A | Aryl-N-hydroxyureas as inhibitors of 5-lipoxygenase and anto-arteriosclerotic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-06-27 | — | — | US | claimed |
| US-5541205-A | ANTIINFLAMMATORY AGENTS; ANTIASTHMA AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-07-30 | — | — | US | disclosed |
| US-5428048-A | Aryl-N-hydroxyureas as inhibitors of 5-lipoxygenase and anto-arteriosclerotic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-06-27 | — | — | US | disclosed |