SCHEMBL9005916

SCHEMBL9005916

Cc1oc(-c2ccccc2)nc1CCOc1cccc(CN(O)C(N)=O)c1

nearest known ligand 0.73

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.73
PPARA Q07869 20/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9174135 0.91 KDR (0.69) PPARGPPARA
SCHEMBL8859196 0.89 PPARG (0.72) PPARGPPARA
SCHEMBL9005925 0.85 PPARG (0.59) PPARGPPARA
SCHEMBL9177905 0.85 PPARG (0.65) PPARGPPARA
SCHEMBL13718226 0.85 PPARG (1.00) PPARGPPARA
SCHEMBL9005919 0.84 PPARG (0.54) PPARGPPARA
SCHEMBL4391054 0.84 PPARG (0.75) PPARGPPARA
SCHEMBL12617516 0.84 PPARG (0.74) PPARGPPARA
SCHEMBL13719277 0.83 PPARG (0.71) PPARGPPARA
SCHEMBL9177062 0.83 PPARG (0.69) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5541205-A ANTIINFLAMMATORY AGENTS; ANTIASTHMA AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1996-07-30 US disclosed
US-5428048-A Aryl-N-hydroxyureas as inhibitors of 5-lipoxygenase and anto-arteriosclerotic agents AMERICAN HOME PRODUCTS CORPORATION (US) 1995-06-27 US disclosed