Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.72 |
| ▸ | PPARA | Q07869 | 17/20 | 0.72 |
| ▸ | PPARD | Q03181 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9156966 | 0.92 | PPARA (0.61) | PPARGPPARAPPARD | |
| SCHEMBL9005900 | 0.91 | PPARG (0.60) | PPARGPPARAPPARD | |
| SCHEMBL9005936 | 0.91 | PPARG (0.64) | PPARGPPARA | |
| SCHEMBL9258855 | 0.91 | FFAR1 (0.67) | PPARGPPARA | |
| SCHEMBL9005916 | 0.89 | PPARG (0.73) | PPARGPPARA | |
| SCHEMBL8686656 | 0.88 | PPARG (0.69) | PPARGPPARAPPARD | |
| SCHEMBL9005899 | 0.88 | PPARA (0.58) | PPARGPPARA | |
| SCHEMBL9005928 | 0.86 | PPARG (0.55) | PPARGPPARA | |
| SCHEMBL9005925 | 0.86 | PPARG (0.59) | PPARGPPARAPPARD | |
| SCHEMBL5451604 | 0.85 | PPARG (0.96) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646168-A | ANTICHOLESTEROL AGENTS | GOLDSTEIN STEVEN WAYNE (US) | 1997-07-08 | — | — | US | disclosed |
| EP-0544696-B1 | HYPOGLYCEMIC HYDROXYUREA DERIVATIVES | PFIZER (US) | 1995-01-11 | — | — | EP | disclosed |
| US-5334604-A | Administering to mammals to lower glucose and/or cholesterol in the blood | PFIZER INC. (US) | 1994-08-02 | — | — | US | disclosed |
| EP-0544696-A1 | HYPOGLYCEMIC HYDROXYUREA DERIVATIVES. | PFIZER HOSPITAL PROD (US) | 1993-06-09 | — | — | EP | disclosed |
| WO-1992003425-A1 | HYPOGLYCEMIC HYDROXYUREA DERIVATIVES | PFIZER INC. (US) | 1992-03-05 | — | — | WO | disclosed |