Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 7/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024212 | 1.00 | PTGDR (0.51) | PTGDRTBXA2REGFRERBB2MMP2 | |
| SCHEMBL9024412 | 0.93 | PTGDR (0.43) | PTGDRTBXA2REGFRERBB2MMP2 | |
| SCHEMBL9006242 | 0.93 | PTGDR (0.43) | PTGDRTBXA2REGFRERBB2MMP2 | |
| SCHEMBL9006209 | 0.93 | PTGDR (0.52) | PTGDRTBXA2RMMP2MMP1MMP3 | |
| SCHEMBL9024183 | 0.93 | PTGDR (0.52) | PTGDRTBXA2RMMP2MMP1MMP3 | |
| SCHEMBL9024128 | 0.93 | TBXA2R (0.49) | PTGDRTBXA2RTBXAS1 | |
| SCHEMBL9006172 | 0.93 | TBXA2R (0.49) | PTGDRTBXA2RTBXAS1 | |
| SCHEMBL9006100 | 0.91 | TBXA2R (0.47) | PTGDRTBXA2REGFRERBB2TBXAS1 | |
| SCHEMBL9024627 | 0.91 | TBXA2R (0.47) | PTGDRTBXA2REGFRERBB2TBXAS1 | |
| SCHEMBL9024027 | 0.90 | TBXA2R (0.47) | PTGDRTBXA2RTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367130-B1 | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-10-02 | — | — | EP | disclosed |
| US-5514701-A | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-07 | — | — | US | disclosed |
| US-5264453-A | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-23 | — | — | US | disclosed |
| US-5130323-A | PYRROLIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-14 | — | — | US | disclosed |
| EP-0367130-A2 | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-05-09 | — | — | EP | disclosed |