Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 11/20 | 0.47 |
| ▸ | STS | P08842 | 2/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024050 | 1.00 | TBXA2R (0.47) | TBXA2RSTSNR1H2TBXAS1PTGDR | |
| SCHEMBL9006258 | 0.95 | TBXA2R (0.47) | TBXA2RSTSNR1H2TBXAS1PTGDR | |
| SCHEMBL9023890 | 0.95 | TBXA2R (0.47) | TBXA2RSTSNR1H2TBXAS1PTGDR | |
| SCHEMBL9024402 | 0.87 | TBXA2R (0.48) | TBXA2RTBXAS1PTGDR | |
| SCHEMBL9006144 | 0.87 | TBXA2R (0.48) | TBXA2RTBXAS1PTGDR | |
| SCHEMBL9006196 | 0.86 | STS (0.52) | TBXA2RSTSNR1H2HTTMCL1 | |
| SCHEMBL9503241 | 0.82 | STS (0.45) | TBXA2RSTSNR1H2HTT | |
| SCHEMBL9503235 | 0.82 | STS (0.45) | TBXA2RSTSNR1H2HTT | |
| SCHEMBL9006155 | 0.79 | STS (0.44) | STSNR1H2 | |
| SCHEMBL9006182 | 0.79 | STS (0.44) | STSNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367130-B1 | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-10-02 | — | — | EP | disclosed |
| US-5514701-A | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-07 | — | — | US | disclosed |
| US-5130323-A | PYRROLIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-14 | — | — | US | disclosed |
| EP-0367130-A2 | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-05-09 | — | — | EP | disclosed |