Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 10/20 | 0.48 |
| ▸ | PTGDR | Q13258 | 12/20 | 0.45 |
| ▸ | PTGIR | P43119 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9006144 | 1.00 | TBXA2R (0.48) | TBXA2RPTGDRPTGIRTBXAS1 | |
| SCHEMBL9023890 | 0.92 | TBXA2R (0.47) | TBXA2RPTGDRTBXAS1 | |
| SCHEMBL9006258 | 0.92 | TBXA2R (0.47) | TBXA2RPTGDRTBXAS1 | |
| SCHEMBL9024050 | 0.87 | TBXA2R (0.47) | TBXA2RPTGDRTBXAS1 | |
| SCHEMBL9006203 | 0.87 | TBXA2R (0.47) | TBXA2RPTGDRTBXAS1 | |
| SCHEMBL9503238 | 0.85 | NR1H2 (0.46) | — | |
| SCHEMBL10701160 | 0.85 | NR1H2 (0.46) | — | |
| SCHEMBL9507014 | 0.85 | NR1H2 (0.46) | — | |
| SCHEMBL9006256 | 0.81 | ABCB1 (0.42) | — | |
| SCHEMBL9006249 | 0.81 | ABCB1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367130-B1 | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-10-02 | — | — | EP | disclosed |
| US-5264453-A | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-23 | — | — | US | disclosed |
| US-5130323-A | PYRROLIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-14 | — | — | US | disclosed |
| EP-0367130-A2 | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-05-09 | — | — | EP | disclosed |