Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 4/20 | 0.36 |
| ▸ | CNR2 | P34972 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octrizole SCHEMBL29349945 | 0.86 | NPC1 (0.56) | NPC1RAB9ALMNASHBGCYP3A4 | |
| Octrizole SCHEMBL15508 | 0.86 | NPC1 (0.56) | NPC1RAB9ALMNASHBGCYP3A4 | |
| Octrizole SCHEMBL28983126 | 0.86 | NPC1 (0.56) | NPC1RAB9ALMNASHBGCYP3A4 | |
| SCHEMBL9115616 | 0.85 | NPC1 (0.36) | NPC1RAB9ALMNASHBGCYP3A4 | |
| Octrizole SCHEMBL30315837 | 0.85 | NPC1 (0.55) | NPC1RAB9ALMNASHBGCYP3A4 | |
| SCHEMBL9006433 | 0.84 | CNR1 (0.57) | NPC1RAB9ALMNACNR1CNR2 | |
| SCHEMBL28595118 | 0.83 | PTPN5 (0.36) | NPC1RAB9ALMNASHBGCYP3A4 | |
| SCHEMBL7592852 | 0.83 | NPC1 (0.42) | NPC1RAB9ALMNASHBGCYP3A4 | |
| SCHEMBL7909025 | 0.83 | NPC1 (0.46) | NPC1RAB9ALMNASHBGCYP3A4 | |
| Octrizole SCHEMBL5547097 | 0.82 | NPC1 (0.52) | NPC1RAB9ALMNASHBGCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556980-A | LIGHT STABILIZERS FOR POLYMERS, PAINTS AND WAXES | SUMITOMO CHEMICAL CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |