Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9006581 | 0.83 | TYR (0.50) | TYRMAPTHTTALOX15TP53 | |
| SCHEMBL1275210 | 0.82 | ESR1 (0.53) | ESR1ESR2GABRA1GABRB2MAPT | |
| SCHEMBL9006698 | 0.79 | TYR (0.67) | TYRESR1ESR2MAPTHTT | |
| SCHEMBL28688935 | 0.79 | TYR (0.39) | TYRMAPTHTTALOX15TP53 | |
| SCHEMBL7041344 | 0.78 | GRIN2D (0.36) | ESR1ESR2GABRA1GABRB2MAPT | |
| SCHEMBL10653612 | 0.77 | TYR (0.34) | TYR | |
| SCHEMBL9006562 | 0.77 | EGFR (0.46) | MAPTALOX15TP53KDM4ELMNA | |
| SCHEMBL29492456 | 0.76 | TYR (0.65) | TYRMAPTHTTALOX15TP53 | |
| SCHEMBL16528083 | 0.76 | HSD17B1 (0.50) | TYRESR1ESR2GABRA1GABRB2 | |
| SCHEMBL40375 | 0.76 | TYR (0.65) | TYRMAPTHTTALOX15TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623341-B1 | Use of 4-thioresorcin derivatives in skin whitening cosmetic or dermopharmaceutical compositions | OREAL (FR) | 1996-10-16 | — | — | EP | claimed |