SCHEMBL9006578

SCHEMBL9006578

O=C(Oc1ccc2oc(=O)ccc2c1)c1ccc(OC(F)=C(F)F)cc1

nearest known ligand 0.70

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA12 O43570 10/20 0.70
CA9 Q16790 10/20 0.70
KMT2A Q03164 7/20 0.58
GBA1 P04062 2/20 0.58
POLB P06746 2/20 0.57
MEN1 O00255 3/20 0.51
CYP2A6 P11509 1/20 0.49
KDM4E B2RXH2 2/20 0.46
GLA P06280 2/20 0.46
GAA P10253 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.43
CA1 P00915 2/20 0.43
CA4 P22748 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9006755 0.91 KMT2A (0.70) CA12CA9KMT2AGBA1POLB
SCHEMBL9006645 0.89 CA9 (0.66) CA12CA9KMT2APOLBMEN1
SCHEMBL9006400 0.80 CA12 (0.65) CA12CA9KMT2AGBA1POLB
SCHEMBL15842550 0.78 CA9 (0.75) CA12CA9KMT2AGBA1POLB
SCHEMBL9006494 0.76 CA9 (0.50) CA12CA9POLBCYP2A6KDM4E
SCHEMBL9006604 0.76 CYP2A6 (0.47) CA12CA9KMT2AGBA1POLB
SCHEMBL9006707 0.76 CYP2A6 (0.50) CA12CA9KMT2AGBA1POLB
Hydrochloric Acid SCHEMBL31460331 0.75 CA9 (0.63) CA12CA9KMT2AGBA1POLB
SCHEMBL6743424 0.75 KMT2A (0.78) CA12CA9KMT2AGBA1POLB
SCHEMBL16283612 0.74 CA12 (1.00) CA12CA9KMT2AGBA1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5489623-A APPLYING POLYMER TO SURFACE, EXPOSING TO INCIDENT PHOTONICRADIATION TO RENDER PORTIONS LESS SOLUBLE OR DISPERSIBLE THE DOW CHEMICAL COMPANY (US) 1996-02-06 US claimed
EP-0676062-A1 PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS THE DOW CHEMICAL COMPANY (US) 1995-10-11 EP claimed
US-5426164-A Solvent and chemical resistant coatings and photoresists; photocuring of perfluorovinyl polymers containing photo active sites; cyclization THE DOW CHEMICAL COMPANY (US) 1995-06-20 US claimed
WO-1994015258-A1 PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS THE DOW CHEMICAL COMPANY (US) 1994-07-07 WO claimed
US-5489623-A APPLYING POLYMER TO SURFACE, EXPOSING TO INCIDENT PHOTONICRADIATION TO RENDER PORTIONS LESS SOLUBLE OR DISPERSIBLE THE DOW CHEMICAL COMPANY (US) 1996-02-06 US disclosed
EP-0676062-A1 PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS THE DOW CHEMICAL COMPANY (US) 1995-10-11 EP disclosed
US-5426164-A Solvent and chemical resistant coatings and photoresists; photocuring of perfluorovinyl polymers containing photo active sites; cyclization THE DOW CHEMICAL COMPANY (US) 1995-06-20 US disclosed
WO-1994015258-A1 PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS THE DOW CHEMICAL COMPANY (US) 1994-07-07 WO disclosed