SCHEMBL9006798

SCHEMBL9006798

COC(=O)COc1ccc2c(c1)C[C@H](NC[C@@H](O)c1cccc(Cl)c1)CC2

nearest known ligand 0.84

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADRB3 P13945 15/20 0.83
ADRB1 P08588 4/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6441833 1.00 ADRB3 (0.83) ADRB3ADRB1
Hydrochloric Acid SCHEMBL9317518 0.99 ADRB3 (0.82) ADRB3ADRB1
Amibegron SCHEMBL2052478 0.92 ADRB3 (0.91) ADRB3ADRB1
Amibegron SCHEMBL6931932 0.92 ADRB3 (0.91) ADRB3ADRB1
Amibegron SCHEMBL29373533 0.92 ADRB3 (0.91) ADRB3ADRB1
Amibegron SCHEMBL9006793 0.92 ADRB3 (0.91) ADRB3ADRB1
Amibegron SCHEMBL5200899 0.92 ADRB3 (0.91) ADRB3ADRB1
Amibegron SCHEMBL3898164 0.92 ADRB3 (0.91) ADRB3ADRB1
Amibegron SCHEMBL8765764 0.92 ADRB3 (0.91) ADRB3ADRB1
Amibegron SCHEMBL3824162 0.92 ADRB3 (0.91) ADRB3ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0403360-B1 Use of phenylethanolamines for the preparation of a medicament for treating ophthalmologic disorders SANOFI SA (FR) 1996-10-16 EP claimed
EP-0303546-B1 O-alkylation process for N-(hydroxy)aralkyl phenyl ethanol amines SANOFI SA (FR) 1994-12-28 EP claimed