Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 11/20 | 0.86 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | HTR1A | P08908 | 2/20 | 0.59 |
| ▸ | DRD3 | P35462 | 2/20 | 0.59 |
| ▸ | HTR2B | P41595 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10731594 | 1.00 | ADRB2 (0.86) | ADRB2MEN1KMT2AOPRK1ADRA1A | |
| SCHEMBL9006843 | 1.00 | ADRB2 (0.86) | ADRB2MEN1KMT2AOPRK1ADRA1A | |
| SCHEMBL11480783 | 1.00 | ADRB2 (0.86) | ADRB2MEN1KMT2AOPRK1ADRA1A | |
| SCHEMBL9006836 | 1.00 | ADRB2 (0.86) | ADRB2MEN1KMT2AOPRK1ADRA1A | |
| SCHEMBL9006822 | 1.00 | ADRB2 (0.86) | ADRB2MEN1KMT2AOPRK1ADRA1A | |
| SCHEMBL11480791 | 1.00 | ADRB2 (0.86) | ADRB2MEN1KMT2AOPRK1ADRA1A | |
| Hydrochloric Acid SCHEMBL10560977 | 0.99 | ADRB2 (0.84) | ADRB2MEN1KMT2AOPRK1ADRA1A | |
| Hydrochloric Acid SCHEMBL11462907 | 0.99 | ADRB2 (0.84) | ADRB2MEN1KMT2AOPRK1ADRA1A | |
| Hydrochloric Acid SCHEMBL11462909 | 0.99 | ADRB2 (0.84) | ADRB2MEN1KMT2AOPRK1ADRA1A | |
| Acetic Acid SCHEMBL10562052 | 0.95 | ADRB2 (0.78) | ADRB2MEN1KMT2AOPRK1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0403360-B1 | Use of phenylethanolamines for the preparation of a medicament for treating ophthalmologic disorders | SANOFI SA (FR) | 1996-10-16 | — | — | EP | claimed |
| US-5236951-A | Administering a phenylethanolamine derivative | SANOFI (FR) | 1993-08-17 | — | — | US | claimed |
| EP-0255415-B1 | USE OF PHENYLETHANOLAMINES FOR THE PREPARATION OF MEDICAMENTS ACTING ON GASTROINTESTINAL TROUBLES | ELF SANOFI (FR) | 1993-04-14 | — | — | EP | claimed |
| US-5002946-A | Gastrointestinal diseases associated with smooth muscle contractions | SANOFI (FR) | 1991-03-26 | — | — | US | claimed |
| EP-0255415-A2 | Use of phenylethanolamines for the preparation of medicaments acting on gastrointestinal troubles | ELF SANOFI (FR) | 1988-02-03 | — | — | EP | claimed |
| EP-0403360-B1 | Use of phenylethanolamines for the preparation of a medicament for treating ophthalmologic disorders | SANOFI SA (FR) | 1996-10-16 | — | — | EP | disclosed |
| US-5236951-A | Administering a phenylethanolamine derivative | SANOFI (FR) | 1993-08-17 | — | — | US | disclosed |
| EP-0255415-B1 | USE OF PHENYLETHANOLAMINES FOR THE PREPARATION OF MEDICAMENTS ACTING ON GASTROINTESTINAL TROUBLES | ELF SANOFI (FR) | 1993-04-14 | — | — | EP | disclosed |
| US-5002946-A | Gastrointestinal diseases associated with smooth muscle contractions | SANOFI (FR) | 1991-03-26 | — | — | US | disclosed |
| EP-0403360-A2 | Use of phenylethanolamines for the preparation of a medicament for treating ophthalmologic disorders | SANOFI (FR) | 1990-12-19 | — | — | EP | disclosed |
| US-4652679-A | Aziridine and phenethanolamine derivatives having antiobesity and anti-hyperglycaemic acitivity | HOFFMANN-LA ROCHE INC. (US) | 1987-03-24 | — | — | US | disclosed |