Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 14/20 | 1.00 |
| ▸ | ADRB2 | P07550 | 11/20 | 1.00 |
| ▸ | ADRB1 | P08588 | 8/20 | 1.00 |
| ▸ | GLA | P06280 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.83 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.83 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.83 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.83 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.83 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.83 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.83 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.80 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.80 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5144149 | 1.00 | ADRB3 (1.00) | ADRB3ADRB2ADRB1GLACYP2D6 | |
| SCHEMBL5144151 | 1.00 | ADRB3 (1.00) | ADRB3ADRB2ADRB1GLACYP2D6 | |
| SCHEMBL5144153 | 1.00 | ADRB3 (1.00) | ADRB3ADRB2ADRB1GLACYP2D6 | |
| SCHEMBL4611391 | 1.00 | ADRB3 (1.00) | ADRB3ADRB2ADRB1GLACYP2D6 | |
| Bromide SCHEMBL29460100 | 0.99 | ADRB3 (0.98) | ADRB3ADRB2ADRB1GLACYP2D6 | |
| Bromide SCHEMBL9317314 | 0.99 | ADRB3 (0.98) | ADRB3ADRB2ADRB1GLACYP2D6 | |
| Bromide SCHEMBL9799484 | 0.99 | ADRB3 (0.98) | ADRB3ADRB2ADRB1GLACYP2D6 | |
| Trifluoroacetic Acid SCHEMBL9318455 | 0.94 | ADRB3 (0.89) | ADRB3ADRB2ADRB1GLACYP2D6 | |
| SCHEMBL9812022 | 0.91 | ADRB3 (0.84) | ADRB3ADRB2ADRB1GLACYP2D6 | |
| SCHEMBL9436811 | 0.91 | ADRB3 (0.84) | ADRB3ADRB2ADRB1GLACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0403360-B1 | Use of phenylethanolamines for the preparation of a medicament for treating ophthalmologic disorders | SANOFI SA (FR) | 1996-10-16 | — | — | EP | claimed |
| EP-0255415-B1 | USE OF PHENYLETHANOLAMINES FOR THE PREPARATION OF MEDICAMENTS ACTING ON GASTROINTESTINAL TROUBLES | ELF SANOFI (FR) | 1993-04-14 | — | — | EP | claimed |
| US-5002946-A | Gastrointestinal diseases associated with smooth muscle contractions | SANOFI (FR) | 1991-03-26 | — | — | US | claimed |
| EP-0403360-A2 | Use of phenylethanolamines for the preparation of a medicament for treating ophthalmologic disorders | SANOFI (FR) | 1990-12-19 | — | — | EP | claimed |
| EP-0255415-A2 | Use of phenylethanolamines for the preparation of medicaments acting on gastrointestinal troubles | ELF SANOFI (FR) | 1988-02-03 | — | — | EP | claimed |
| US-4803293-A | Tertiary amines | BEECHAM GROUP PLC (GB) | 1989-02-07 | — | — | US | disclosed |
| EP-0142102-B1 | TERTIARY AMINES | BEECHAM GROUP PLC (GB) | 1987-09-23 | — | — | EP | disclosed |
| EP-0164700-A2 | Bis(beta-hydroxy phenethyl)amines | BEECHAM GROUP PLC (GB) | 1985-12-18 | — | — | EP | disclosed |