Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.85 |
| ▸ | TSHR | P16473 | 2/20 | 0.85 |
| ▸ | LMNA | P02545 | 2/20 | 0.85 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.85 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL27941911 | 1.00 | ACHE (0.85) | ACHETSHRLMNAALOX12TDP1 | |
| Toluene SCHEMBL5353703 | 1.00 | ACHE (0.85) | ACHETSHRLMNAALOX12TDP1 | |
| Toluene SCHEMBL9672173 | 1.00 | ACHE (0.85) | ACHETSHRLMNAALOX12TDP1 | |
| Toluene SCHEMBL352057 | 1.00 | — | — | |
| Toluene SCHEMBL11010267 | 1.00 | ACHE (0.85) | ACHETSHRLMNAALOX12TDP1 | |
| Toluene SCHEMBL9720616 | 1.00 | ACHE (0.85) | ACHETSHRLMNAALOX12TDP1 | |
| Toluene SCHEMBL28884246 | 1.00 | ACHE (0.85) | ACHETSHRLMNAALOX12TDP1 | |
| Toluene SCHEMBL10573085 | 0.96 | ACHE (0.79) | ACHETSHRLMNAALOX12TDP1 | |
| P-Xylene SCHEMBL28284063 | 0.96 | ACHE (0.79) | ACHETSHRLMNAALOX12TDP1 | |
| Toluene SCHEMBL10609474 | 0.96 | ACHE (0.79) | ACHETSHRLMNAALOX12TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736005-A1 | AMINOCARBOXYLIC ACID AMIDES, PROCESS FOR PREPARING THE SAME AND THEIR USE AS ANTI-ARRHYTHMIC AGENTS | ARZNEIMITTELWERK DRESDEN GmbH, FACHBEREICH PATENTE (DE) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995018099-A1 | AMINOCARBOXYLIC ACID AMIDES, PROCESS FOR PREPARING THE SAME AND THEIR USE AS ANTI-ARRHYTHMIC AGENTS | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1995-07-06 | — | — | WO | disclosed |