Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PTPRZ1 | P23471 | 4/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KCNK2 | O95069 | 4/20 | 0.32 |
| ▸ | KCNK10 | P57789 | 3/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL901109 | 0.83 | ALDH1A1 (0.43) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL16555940 | 0.75 | ALDH1A1 (0.43) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL900729 | 0.75 | SMN1; SMN2 (0.49) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL15068206 | 0.75 | KCNK2 (0.43) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL12474320 | 0.75 | KDM4E (0.39) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL10430860 | 0.73 | KDM4E (0.42) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL30410247 | 0.71 | KCNK2 (0.43) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL901110 | 0.71 | SMN1; SMN2 (0.49) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL16667141 | 0.71 | KCNK2 (0.43) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL3627129 | 0.71 | ALDH1A1 (0.54) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621922-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041858-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |