Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.72 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PTGIR | P43119 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8812217 | 0.99 | ADORA1 (0.73) | ADORA1HTTFAAHHSD17B10CYP1A2 | |
| SCHEMBL8808149 | 0.96 | ADORA1 (0.77) | ADORA1HTTFAAHHSD17B10CYP1A2 | |
| SCHEMBL8807647 | 0.87 | ADORA1 (0.94) | ADORA1HTTHSD17B10MAPK1PTGIR | |
| SCHEMBL9007309 | 0.86 | ADORA1 (0.52) | ADORA1HTTFAAHHSD17B10CYP1A2 | |
| SCHEMBL7290695 | 0.85 | ADORA1 (0.62) | ADORA1HTTHSD17B10CYP1A2ALDH1A1 | |
| SCHEMBL19829272 | 0.85 | ADORA1 (0.86) | ADORA1HTTHSD17B10EGFRMAPK1 | |
| SCHEMBL7292843 | 0.84 | ADORA1 (0.72) | ADORA1HTTHSD17B10CYP1A2EGFR | |
| SCHEMBL7303206 | 0.84 | ADORA1 (0.74) | ADORA1MAPK1IGF1R | |
| SCHEMBL7301601 | 0.84 | ADORA1 (0.74) | ADORA1MAPK1IGF1R | |
| SCHEMBL7290705 | 0.84 | ADORA1 (0.74) | ADORA1MAPK1IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8099976-A | — | — | None | — | — | JP | disclosed |
| JP-H0899976-A | PYRAZOLOPYRIDINE AND ADENOSINE ANTAGONIST CONTAINING THE SAME | FUJISAWA PHARMACEUT CO LTD | 1996-04-16 | — | — | JP | disclosed |