Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | PTPRF | P10586 | 1/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 2/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11317000 | 0.78 | HTT (0.49) | MAPTMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL900753 | 0.78 | MAPT (0.66) | PTPRFPTPN2PTPN1PTPN11MAPT | |
| SCHEMBL22624739 | 0.78 | APP (0.65) | MAOBPTPRFPTPN2PTPN1PTPN11 | |
| SCHEMBL6819384 | 0.78 | PTPRF (0.59) | MAOBPTPRFPTPN2PTPN1PTPN11 | |
| SCHEMBL8168049 | 0.76 | CA12 (0.41) | MAPTAPPMEN1KMT2AALDH1A1 | |
| SCHEMBL14259387 | 0.76 | PTPRF (0.56) | MAOBPTPRFPTPN2PTPN1PTPN11 | |
| SCHEMBL7238917 | 0.74 | SMN1; SMN2 (0.53) | MAOBPTPRFPTPN2PTPN1PTPN11 | |
| SCHEMBL23041348 | 0.73 | KMT2A (0.54) | MAPTMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL29625925 | 0.73 | KMT2A (0.54) | MAPTMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL7338580 | 0.73 | PTPRF (0.69) | MAOBPTPRFPTPN2PTPN1PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621885-A1 | METHODS OF SYNTHESIZING 2-METHOXYMETHYL-1,4-BENZENEDIAMINE | The Procter and Gamble Company (US) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012044758-A1 | METHODS OF SYNTHESIZING 2-METHOXYMETHYL-1,4-BENZENEDIAMINE | THE PROCTER & GAMBLE COMPANY (US) | 2012-04-05 | — | — | WO | disclosed |