SCHEMBL900753

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27376900	0.83	MAPT (0.67)	MAPTKMT2AMEN1CRHBPCRHR2
	SCHEMBL8370786	0.81	MAPT (0.64)	MAPTKMT2AMEN1CRHBPCRHR2
	SCHEMBL2059682	0.80	MAPT (1.00)	MAPTKMT2AMEN1CRHBPCRHR2
	SCHEMBL4860161	0.79	TSHR (0.59)	MAPTKMT2AMEN1GAAHTT
	SCHEMBL27477066	0.79	MAPT (0.65)	MAPTKMT2AMEN1CRHBPCRHR2
	SCHEMBL9395569	0.78	MAPT (0.72)	MAPTKMT2AMEN1CRHBPCRHR2
	SCHEMBL900754	0.78	MAOB (0.55)	MAPTKMT2AMEN1CRHBPCRHR2
	SCHEMBL14003601	0.77	ALDH1A1 (0.58)	MAPTKMT2AMEN1CYP1A2CYP2C9
	SCHEMBL9395627	0.77	MAPT (0.70)	MAPTKMT2AMEN1CRHBPCRHR2
	SCHEMBL3750282	0.77	MEN1 (0.70)	MAPTKMT2AMEN1CRHBPCRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.