Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.65 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.65 |
| ▸ | PPARG | P37231 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9007499 | 0.96 | AGTR1 (0.65) | AGTR1AGTR2PPARG | |
| SCHEMBL9007500 | 0.94 | AGTR1 (0.68) | AGTR1AGTR2PPARG | |
| SCHEMBL9007510 | 0.92 | AGTR1 (0.60) | AGTR1AGTR2PPARG | |
| SCHEMBL9007561 | 0.89 | AGTR1 (0.60) | AGTR1AGTR2PPARG | |
| SCHEMBL9396659 | 0.89 | AGTR1 (0.62) | AGTR1AGTR2PPARG | |
| SCHEMBL9007540 | 0.88 | AGTR1 (0.61) | AGTR1AGTR2PPARG | |
| SCHEMBL9007461 | 0.88 | AGTR1 (0.63) | AGTR1AGTR2PPARG | |
| SCHEMBL9007478 | 0.87 | AGTR1 (0.67) | AGTR1AGTR2PPARG | |
| SCHEMBL9007505 | 0.87 | AGTR1 (0.62) | AGTR1AGTR2PPARG | |
| SCHEMBL9007528 | 0.87 | AGTR1 (0.62) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506361-A | ACTS BOTH AS AN ANGIOTENSIN II ANTAGONIST AND A LIPIDPEROXIDATION INHIBITOR | THEUPJOHN COMPANY (US) | 1996-04-09 | — | — | US | claimed |
| WO-1992019211-A2 | IMIDAZOBENZOQUINONES AND COMPOSITION FOR PREVENTING OR TREATING HYPERTENSION OR CONGESTIVE HEART FAILURE CONTAINING THE SAME | THE UPJOHN COMPANY (US) | 1992-11-12 | — | — | WO | claimed |
| US-5506361-A | ACTS BOTH AS AN ANGIOTENSIN II ANTAGONIST AND A LIPIDPEROXIDATION INHIBITOR | THEUPJOHN COMPANY (US) | 1996-04-09 | — | — | US | disclosed |
| EP-0586466-A1 | IMIDAZOBENZOQUINONES AND COMPOSITION FOR PREVENTING OR TREATING HYPERTENSION OR CONGESTIVE HEART FAILURE CONTAINING THE SAME | PHARMACIA & UPJOHN COMPANY (US) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992019211-A2 | IMIDAZOBENZOQUINONES AND COMPOSITION FOR PREVENTING OR TREATING HYPERTENSION OR CONGESTIVE HEART FAILURE CONTAINING THE SAME | THE UPJOHN COMPANY (US) | 1992-11-12 | — | — | WO | disclosed |