Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | IL6ST | P40189 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 8/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9007611 | 1.00 | PPARA (0.44) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL17497683 | 1.00 | PPARA (0.44) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL19899197 | 1.00 | PPARA (0.44) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL19899230 | 1.00 | PPARA (0.44) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL19899198 | 1.00 | PPARA (0.44) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL2273418 | 0.91 | PPARA (0.42) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL7050316 | 0.91 | PPARA (0.42) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL5966517 | 0.91 | FAAH (0.42) | PPARANAAAFAAH | |
| SCHEMBL5966519 | 0.91 | FAAH (0.42) | PPARANAAAFAAH | |
| SCHEMBL12418053 | 0.90 | PPARA (0.42) | PPARAIL6STNAAAIDH1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5569762-A | Asymmetric synthesis of intermediates for retroviral protease inhibitor compounds | AMERICAN CYANAMID COMPANY (US) | 1996-10-29 | — | — | US | disclosed |
| US-5428167-A | Asymmetric synthesis of intermediates for retroviral protease inhibitor compounds | AMERICAN CYANAMID COMPANY (US) | 1995-06-27 | — | — | US | disclosed |