Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11435348 | 1.00 | LMNA (0.33) | LMNACHRM3CYP2D6MEN1HRH1 | |
| SCHEMBL8608891 | 0.80 | HTR2C (0.38) | ALDH1A1TSHR | |
| SCHEMBL5175216 | 0.78 | MAPK1 (0.34) | LMNACHRM3CYP2D6MEN1HRH1 | |
| SCHEMBL749097 | 0.75 | KCNN4 (0.38) | LMNACHRM3CYP2D6MEN1HRH1 | |
| SCHEMBL3502282 | 0.75 | KCNN4 (0.38) | LMNACHRM3CYP2D6MEN1HRH1 | |
| SCHEMBL11328095 | 0.75 | KCNN4 (0.38) | LMNACHRM3CYP2D6MEN1HRH1 | |
| SCHEMBL10907499 | 0.73 | CYP2D6 (0.41) | LMNACHRM3CYP2D6MEN1HRH1 | |
| SCHEMBL2464761 | 0.73 | CYP2D6 (0.36) | LMNACHRM3CYP2D6MEN1HRH1 | |
| SCHEMBL18788591 | 0.73 | CYP2D6 (0.41) | LMNACHRM3CYP2D6MEN1HRH1 | |
| SCHEMBL8607528 | 0.72 | CHRM3 (0.33) | CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216331-A | Use of chiral rhodium-diphosphine catalyst capable of catalytic reduction of a tetramisole precursor to give a significant excess of the desired S-(-) isomer levamisole | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | claimed |
| US-4166824-A | Chiral rhodium-diphosphine catalyst capable of catalytic reduction of a tetramisole precursor to give a significant excess of the desired S-(-)isomer, levamisole | AMERICAN CYANAMID COMPANY (US) | 1979-09-04 | — | — | US | claimed |
| JP-55100331-A | — | — | None | — | — | JP | disclosed |
| US-5530162-A | Process for the hydrogenation of aryl phosphines and products obtained therefrom | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1996-06-25 | — | — | US | disclosed |
| US-4370258-A | PLATINUM CATALYST, INB METAL HALIDE ASSISTANT CATALYST AND BIDENTATE LIGAND PROMOTER | AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) | 1983-01-25 | — | — | US | disclosed |
| US-4283563-A | HYDROFORMYLATION OF OLEFINS USING A PLATINUM-PHOSPHINE COMPLEX CATALYST | AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) | 1981-08-11 | — | — | US | disclosed |
| US-4229381-A | HYDROFORMYLATION OF OLEFINS; PLATINUM CATALYST; BIDENTATE LIGAND | AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) | 1980-10-21 | — | — | US | disclosed |
| US-4216331-A | Use of chiral rhodium-diphosphine catalyst capable of catalytic reduction of a tetramisole precursor to give a significant excess of the desired S-(-) isomer levamisole | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |
| JP-S55100331-A | PREPARATION OF ALDEHYDE | AGENCY OF IND SCIENCE & TECHNOL | 1980-07-31 | — | — | JP | disclosed |
| US-4166824-A | Chiral rhodium-diphosphine catalyst capable of catalytic reduction of a tetramisole precursor to give a significant excess of the desired S-(-)isomer, levamisole | AMERICAN CYANAMID COMPANY (US) | 1979-09-04 | — | — | US | disclosed |