Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 14/20 | 0.77 |
| ▸ | ACE | P12821 | 13/20 | 0.77 |
| ▸ | CPA1 | P15085 | 4/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9007742 | 1.00 | MME (0.77) | MMEACECPA1ACE2PTPN1 | |
| SCHEMBL8030332 | 0.95 | MME (0.68) | MMEACEPTPN1 | |
| SCHEMBL8030328 | 0.95 | MME (0.68) | MMEACEPTPN1 | |
| SCHEMBL8028610 | 0.92 | ACE (0.68) | MMEACECPA1ACE2 | |
| SCHEMBL8017382 | 0.90 | MME (0.63) | MMEACECPA1ACE2PTPN1 | |
| SCHEMBL8017386 | 0.90 | MME (0.63) | MMEACECPA1ACE2PTPN1 | |
| SCHEMBL8027312 | 0.88 | ACE (0.61) | MMEACEPTPN1 | |
| SCHEMBL8032863 | 0.87 | MME (1.00) | MMEACECPA1ACE2 | |
| SCHEMBL8033719 | 0.87 | MME (1.00) | MMEACECPA1ACE2 | |
| SCHEMBL8027291 | 0.87 | MME (1.00) | MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |