Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 12/20 | 0.68 |
| ▸ | MME | P08473 | 15/20 | 0.67 |
| ▸ | CPA1 | P15085 | 1/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.53 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8028710 | 0.92 | ACE (0.80) | ACEMMECPA1ACE2 | |
| SCHEMBL9007746 | 0.92 | MME (0.77) | ACEMMECPA1ACE2 | |
| SCHEMBL9007742 | 0.92 | MME (0.77) | ACEMMECPA1ACE2 | |
| SCHEMBL8027149 | 0.91 | ACE (0.58) | ACEMMECPA1ACE2 | |
| SCHEMBL8027344 | 0.89 | MME (0.85) | ACEMMECPA1ACE2 | |
| SCHEMBL8027141 | 0.88 | MME (0.63) | ACEMMECPA1ACE2 | |
| SCHEMBL8030332 | 0.87 | MME (0.68) | ACEMME | |
| SCHEMBL8030328 | 0.87 | MME (0.68) | ACEMME | |
| SCHEMBL27463686 | 0.86 | ACE (0.52) | ACEMMECPA1ACE2PTGES | |
| SCHEMBL8027312 | 0.84 | ACE (0.61) | ACEMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| CN-1138321-A | 1, 3-dialkyl urea derivative with hydrocarbon group | SANTAN PHARMACEUTICAL CO LTD (JP) | 1996-12-18 | — | — | CN | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |