Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRZ1 | P23471 | 3/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL900562 | 0.82 | PTPRZ1 (0.33) | PTPRZ1PTPN1 | |
| SCHEMBL20411965 | 0.79 | KDM4E (0.42) | PTPRZ1PTPN1KDM4EALDH1A1TDP1 | |
| SCHEMBL12474309 | 0.78 | PTPRZ1 (0.34) | PTPRZ1PTPN1KDM4EALDH1A1TDP1 | |
| SCHEMBL900700 | 0.74 | KDM4E (0.35) | PTPRZ1PTPN1KDM4EALDH1A1TDP1 | |
| SCHEMBL148109 | 0.73 | IDO1 (0.46) | — | |
| SCHEMBL5422754 | 0.73 | PTPRZ1 (0.41) | PTPRZ1PTPN1KDM4EALDH1A1TDP1 | |
| SCHEMBL5404852 | 0.71 | PTPRZ1 (0.61) | PTPRZ1PTPN1KDM4EALDH1A1TDP1 | |
| SCHEMBL25326158 | 0.69 | KDM4E (0.35) | PTPRZ1PTPN1KDM4EALDH1A1TDP1 | |
| SCHEMBL153038 | 0.69 | IDO1 (0.41) | KDM4EALDH1A1 | |
| SCHEMBL900702 | 0.69 | TP53 (0.36) | PTPRZ1PTPN1KDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621922-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041858-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |