Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16707569 | 0.86 | ALDH1A1 (0.46) | TP53KDM4EALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL20411965 | 0.84 | KDM4E (0.42) | KDM4EALDH1A1TDP1SMN1; SMN2PTPN1 | |
| SCHEMBL18432757 | 0.77 | ACHE (0.36) | ALDH1A1ACHERAPGEF4 | |
| SCHEMBL16483005 | 0.77 | RAPGEF4 (0.39) | TP53KDM4EALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL12954435 | 0.75 | ACHE (0.37) | ACHERAPGEF4 | |
| SCHEMBL25326158 | 0.74 | KDM4E (0.35) | KDM4EALDH1A1TDP1PTPN1PTPRZ1 | |
| SCHEMBL900700 | 0.74 | KDM4E (0.35) | KDM4EALDH1A1TDP1PTPN1PTPRZ1 | |
| SCHEMBL15787658 | 0.74 | PTPRZ1 (0.36) | TP53KDM4EALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL21233669 | 0.72 | FFAR4 (0.37) | TP53KDM4EALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL12474309 | 0.71 | PTPRZ1 (0.34) | KDM4EALDH1A1TDP1PTPN1PTPRZ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621922-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041858-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |