Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 3/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.39 |
| ▸ | LTA4H | P09960 | 3/20 | 0.38 |
| ▸ | PPID | Q08752 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9007849 | 0.87 | PTGS1 (0.59) | GLO1PTGS1GSTK1NOD1LTA4H | |
| SCHEMBL9007888 | 0.85 | GLO1 (0.50) | GLO1PTGS1GSTK1NOD1 | |
| SCHEMBL4452894 | 0.85 | GLO1 (0.50) | GLO1PTGS1GSTK1NOD1 | |
| SCHEMBL628352 | 0.80 | GLO1 (0.49) | GLO1PTGS1GSTK1NOD1 | |
| Bromide SCHEMBL20874163 | 0.80 | GLO1 (0.46) | GLO1PTGS1GSTK1ALDH1A1NOD1 | |
| Bromide SCHEMBL20874309 | 0.79 | GLO1 (0.45) | GLO1PTGS1GSTK1ALDH1A1NOD1 | |
| Bromide SCHEMBL20874322 | 0.79 | GLO1 (0.47) | GLO1PTGS1GSTK1NOD1 | |
| Bromide SCHEMBL20874235 | 0.79 | GLO1 (0.46) | GLO1PTGS1GSTK1NOD1LTA4H | |
| Bromide SCHEMBL20874255 | 0.79 | GLO1 (0.45) | GLO1PTGS1GSTK1NOD1PPID | |
| SCHEMBL19694411 | 0.79 | GLO1 (0.42) | GLO1PTGS1GSTK1ALDH1A1NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536231-B1 | A PROCESS FOR THE PREPARATION OF GLUTATHIONE S-ACYL DERIVATIVES AND COMPOUNDS OBTAINED FROM SAID PROCESS | BOEHRINGER MANNHEIM ITALIA (IT) | 1996-10-23 | — | — | EP | disclosed |
| US-5382679-A | Process for the preparation of glutathione S-acyl derivatives, compounds obtained from said process and an intermediate useful for the preparation thereof | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1995-01-17 | — | — | US | disclosed |
| WO-1992000320-A1 | A PROCESS FOR THE PREPARATION OF GLUTATHIONE S-ACYL DERIVATIVES, COMPOUNDS OBTAINED FROM SAID PROCESS AND AN INTERMEDIATE USEFUL FOR THE PREPARATION THEREOF | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1992-01-09 | — | — | WO | disclosed |